50 Cent once again targeted Diddy, his longtime adversary, following the news of a lawsuit filed by singer Cassie against Diddy. In an Instagram and Twitter post, 50 Cent mocked Diddy, referencing one of his monikers, Brother Love. Cassie's lawsuit accuses Diddy of rape, sex trafficking, and various forms of abuse throughout their romantic and business relationship. Describing Diddy as a "vicious, cruel, and controlling man," Cassie alleges years of abuse and manipulation.

The lawsuit sheds light on their relationship, which began when Cassie was 19, and Diddy signed her to his Bad Boy imprint. Cassie accuses Diddy of exposing her to a lavish, drug-fueled lifestyle and details instances of physical abuse, drug involvement, and sexual exploitation. Cassie, breaking years of silence, expressed her readiness to share her story for herself and other women facing violence and abuse in relationships.