Over the past couple of months, 50 Cent has been at odds with former G-Unit member Game, going at him on his new track "My Life". 50 has also had more than a few choice words for French Montana, jawing back and forth with the Bad Boy Records artist. 

Now 50 has targeted another Bad Boy Records affiliate: James Cruz, who is Diddy's manager. Cruz and 50 have had a rocky past and the G-Unit leader has seemingly re-ignited their differences. While the reasoning behind 50's lash-out is unknown, he didn't hold back, comparing Cruz to a woman and saying in one of his tweets that Cruz acts like one of [Diddy's] girlfriends.

Check out 50 Cent's tweets above and we'll keep you updated on more from this situation.

Source: hiphopdx.com